If you are starting your weight-loss transformation journey or have been trying everything without observing significant results, then you need to look at the status of internal health, i.e.

• Vitamins & Mineral Levels 
  
• Thyroid Hormones 
  
• Adrenal hormones (Cortisol & Testosterone)
  
• Inflammation 
  
• Metabolism & Insulin Resistance 
  
• Allergies & Intolerances
  
• Microbiome (Gut bacteria) 
  

Microbiome has a very crucial role in weight-loss. "Bacteroidetes" are the anti-obesity bacteria whereas "Firmicutes" are obesity-inducers. The ratio of Bacteroids:Firmicutes indicates your propensity towards weight-loss & obesity.  

If you are on special diet plan such as Keto, Paleo, Low-Carb etc, monitoring your biomarkers is very crucial as this type of diets are known to lower thyroid output, throw your hormonal profile off-balance and in-turn causes health conditions such as decreased libido, fertility, sexual function, hair-loss, muscle-loss etc. Regular monitoring is important if you are taking supplements.