HbA1C Test - Indications, Range & Cost

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Glycated hemoglobin A1c is another name for the HbA1c test. It is employed to gauge the body's blood sugar levels. It helps diagnose and treat diabetes mellitus. RBCs include the protein hemoglobin. It gives the blood a vibrant crimson hue. 


Glycated hemoglobin is a result of the interaction between ketoamines. The N-terminal amino acids of the beta polypeptide chain of hemoglobin and blood glucose, or sugar molecules, interact in this way. As a result, blood sugar molecules bind to the hemoglobin protein.

What is HbA1c?

HbA1c is also known as glycosylated hemoglobin (HbA1c). In the past two to three months, this examination is capable of forecasting standard blood sugar levels. Glycohemoglobin, the glycated hemoglobin test, or HbA1c are other names for it. You can't get a full picture of how your medication is functioning from test results from a single day.

Your doctor can diagnose diabetes based on the results of your A1c test. Prediabetes, a condition in which your hemoglobin level is greater than normal but not sufficiently high to be classified as diabetes, can also be diagnosed with it.


There are instances when your A1c readings are sufficient to suggest prediabetes or diabetes. You don't exhibit any signs of either, though. On a subsequent day, your doctor could prescribe another A1c test to prove the diagnosis. Regular use of this test is necessary for diabetics. It can determine if you need to change your diabetic medication.

Importance of HbA1c

HbA1c is a crucial metric for long-term glycemic control. The glycemic history of the previous two to three months can be reflected in it. A trustworthy indicator of persistent hyperglycemia is the HbA1c. Additionally, it has a strong correlation with the likelihood of long-term problems from diabetes. 


High HbA1c is a risk factor for various diseases on its own. These conditions include stroke and coronary heart disease in individuals with or without diabetes. A single HbA1c test can give substantial information, making it a trustworthy biomarker. It is now a crucial indicator for both diabetes diagnosis and prognosis.

HbA1c Normal Range

The sugar or glucose levels during 90 days make up the typical range of HbA1C. Among the variables influencing HbA1C levels include age, sex, BMI, and medical history. These factors may also be accompanied by family history and genetics.

General Guidelines for Adults

The percentages that are frequently used to diagnose diabetes or prediabetes include:


  • Normal: Below 5.7%

  • Prediabetes: 5.7% - 6.4%

  • Diabetes: 6.5% and above


The 6.5% range of adults is considered pre-diabetic. It shows an increased chance of developing type 2 diabetes. Limit alcohol intake and the intake of junk food and high-fat meals. Additionally, maintaining a balanced diet and engaging in physical activity can help lower the chance of diabetes.

By Age

The HbA1C, or blood sugar levels, are significantly influenced by age. Age-related increases in blood sugar levels are common. As people age, their blood sugar levels rise for no particular cause, according to doctors. The HbA1C values by age in India are shown in this chart, which represents the HbA1C normal range.


Age


In Mg/L


HbA1C levels


Below 18 years


117


5.7%


20-39 years


126


6%


40-59 years


140


6.1%


60 years and above


160


6.5%



Up to 7.5% may be a little higher aim for older persons or those with comorbidities.

Why is the HbA1c Test Done?

If you are obese and over 40, or otherwise at high risk for diabetes, your doctor might want to examine you for other health issues before you start having symptoms. It might be necessary to repeat the test or use another kind of test to verify the results.

Purpose

There are several uses for the hemoglobin A1c test.


Diagnosing diabetes and prediabetes 

To determine the reason for health changes, tests, and procedures are used. If you exhibit signs of diabetes, your doctor may prescribe hemoglobin A1c and additional testing. Extreme fatigue and numbness or loss of touch in the hands and feet are some possible symptoms.

Diabetes Monitoring

Your doctor could prescribe this test no less than twice a year if you are identified with diabetes. This helps your doctor gauge how effectively you've managed your blood sugar in the months between visits. Additionally, it enables your physician to modify your course of therapy. It's to reduce your risk of health issues.

Benefits

For the diagnosis and screening of diabetes, the HbA1c test is a reliable method. It requires no fasting and simply requires one blood sample. It yields dependable and consistent outcomes. The primary benefits of regular HbA1c testing are as follows:

Changes in Treatment

Effective diabetes management requires monitoring the effectiveness of therapy. HbA1c level aims will be adjusted by your physician based on your needs and overall health. Safety and efficient management are balanced.

It is recommended that people with stable blood sugar have their HbA1c checked at least twice a year. Three-monthly testing is helpful if your blood sugar is poorly managed or if your therapy has changed. The goal is to guarantee prompt modifications. It is important to do routine HbA1c testing to verify that blood sugar goals are being fulfilled.

Progress Tracking

To effectively manage diabetes, regular HbA1c testing is essential. You should do it every three months. Depending on your stability, it can be lowered to twice a year. Depending on your diabetes type, duration, and general health, your HbA1c goal will change. Monitoring makes it easier to track your development.


Increased findings suggest that therapy modifications or more frequent blood sugar checks may be necessary. Furthermore, the HbA1c test is reasonably priced. It enables frequent monitoring of the test.

HbA1c Levels and Interpretation

The HbA1C findings are expressed as percentages, in contrast to the majority of other blood-tracking glucose tests. Three steps comprise the test results:



  • Below 5.7% - Healthy glucose levels

  • 5.7 to 6.4% - Diabetes risk (prediabetes) increases.

  • 6.5% and higher – Indicates diabetes


For Diabetics

Take the HbA1C test as part of your regular checkup if you have diabetes. A level below 7% is what your doctor will strive for. Likely, the existing diabetes treatment strategy isn't functioning as well as it ought to if the levels are higher than 7%. In certain situations, the present treatment strategy may be upgraded or changed.

Normal HbA1c Levels by Age

Certain circumstances, such as those involving elderly individuals, call for a cautious interpretation of HbA1c test findings. An individual's blood HbA1c level increases with age. Additionally, older age groups have increased risks of prediabetes and diabetes.

Adults Under Forty

These folks often have a level below 5.7%. The goal for diabetes should be less than 7% if you see a doctor and check your blood frequently.

Elderly People (Over 60)

As people age, their HbA1C rises. However, no apparent explanation appears to exist for it. Numerous research provides explanations for the rise. Levels as high as 7.5% may be tolerated by these elderly people. Other health issues can be to blame.

Prediabetes HbA1c Range

A HbA1c measurement ranging from 5. 7 to 6. 5 is considered prediabetic.

Prediabetes Range

The chance of developing Type 2 diabetes is higher in those with a risk of 5.7% to 6.4%. Higher than normal blood glucose levels are a sign of prediabetes.  Heart disease, stroke, and type 2 diabetes can all be caused by prediabetes. It's the most prevalent type of diabetes. Prediabetes is frequently reversible.

Next Steps

Maintaining a healthy lifestyle might help you return to normal blood sugar levels. If nothing else, it can prevent it from increasing to the levels detected in type 2 diabetes. To stop prediabetes from developing into type 2 diabetes, attempt to:

Eat wholesome meals

Starting with a diet rich in fruits, vegetables, and nuts can be beneficial. Consuming whole grains and olive oil reduces the risk of developing prediabetes. Pick foods high in fiber and low in calories and fat. You may achieve your goals by eating a variety of meals. It will be done without sacrificing nutrients or flavor.

Become more active

You can better manage your weight by exercising. In addition to burning sugar for energy, it improves the body's usage of insulin. You have the option of combining moderate and intense exercise.

Get rid of extra weight

The goal should be to reduce your body weight by only 5% to 7% if you are overweight. About 14 pounds (6.4 kilos) is its weight. At 200 pounds (91 kilos), this should be your goal. This greatly reduces the probability of type 2 diabetes. Concentrate on long-term adjustments to your food and exercise routines to maintain a healthy weight.

How is HbA1c Measured?

A blood sample is drawn from a vein using a needle if the test is conducted in a laboratory. A fingerstick serves to draw blood if the test is conducted at home or a doctor's office.

Procedure

You can eat and drink as usual during the HbA1c Test, unlike other blood tests. The HbA1c screening process consists of these easy stages.



  • To make your vein more noticeable, a phlebotomist will wrap a band across your arm.

  • To lower the chance of infection, they will thereafter clean the area with an antiseptic.

  • The blood is then drawn using a sterile needle, which might hurt and sting.

  • After being transferred to a clean collecting tube, the blood sample is delivered to the lab for examination.

  • To halt the bleeding and reduce the likelihood of complications, a bandage will be placed over the pierced location. 


Test Frequency

It is appropriate to have an HbA1c test once every three months. It is intended for those whose diabetes is not well managed or who are altering their treatment plan. A six-monthly testing frequency is recommended for well-managed patients. Additionally, it was determined that HbA1c testing should never be done over four times in just one year. Both people with type I and type II diabetes should follow these guidelines.

Glycosylated Hemoglobin and Its Role

When hemoglobin is irreversibly glycosylated, it is referred to as glycosylated hemoglobin. It evaluates the long-term management of hyperglycemia with insulin treatment. It also differentiates diabetes from fake hyperglycemia.

What is Glycosylated Hemoglobin?

RBCs contain hemoglobin, which is crucial for transporting oxygen across the body's cells. Blood glucose, a kind of sugar, often binds itself to hemoglobin molecules. This indicates that the hemoglobin, commonly known as hemoglobin A1c or HbA1c, has been glycosylated.

Why Measure It?

Most of the person's hemoglobin is glycosylated as their blood sugar levels rise. During the two to three months while the red blood cell is alive, the glucose stays bonded to the hemoglobin. It shows the average glucose levels across the 90–120 day lifetime of red blood cells.

HbA1c Normal Range Chart

The following chart shows the normal range of HbA1c levels in percentage:


Category


HbA1c Level (%)


Normal


Below 5.7%


Prediabetes


5.7% - 6.4%


Diabetes


6.5% and above





Factors Influencing HbA1c Levels

Some risk factors or situations influence the HbA1c test's outcome. We go over a couple of them below:

High HbA1c:

High hemoglobin A1c poses the following health risks:

Inadequate regulation of blood sugar

Complications from diabetes are caused by poor blood sugar management. In certain individuals with type 1 diabetes, the prevalence of compromised kidney and ocular function rose significantly. It occurred sooner when HbA1c was rising. When the HbA1c was less than 7.6%, not one of the patients experienced these issues.

Illness or stress

Higher base HbA1c levels are associated with suicidal thoughts, eating issues, sleep issues, and depression in many diabetics. these elevated HbA1c readings at the 1-year mark. 

Low HbA1c

The following factors are frequently linked to low HbA1c.

Low blood sugar levels

Blood loss, donation, and transfusion are examples of conditions that might artificially lower HbA1c values by reducing the quantity of red blood cells. Hemolysis, the breakdown of red blood cells that can happen in autoimmune disorders and infections, also lowers HbA1c.

Medical disorders such as anemia

Falsely low HbA1c can be caused by some hereditary illnesses, including thalassemia and sickle cell anemia. The test's methodology in the lab will determine this.

Managing HbA1c Levels

The following strategies can help you maintain control over your HbA1C levels:

Alterations in lifestyle:

Choose a wholesome, well-balanced diet that prioritizes whole foods. Your body utilizes insulin more effectively if you exercise regularly. Blood sugar management is improved as a result. To frequently check your blood sugar levels, use a glucose monitor.

Pharmaceuticals:

Follow your doctor's instructions if you're prescribed diabetic medication. Consult your doctor if you need insulin treatment. It is to comprehend how insulin should be administered and tracked. 

Conclusion

A common method for identifying, screening, and treating diabetic individuals is hemoglobin A1c (HbA1c). However, correct patient evaluation requires mastery of the HbA1c test's use and interpretation. Additionally, it is now the accepted test for population-based research. It is used to assess how glycemic control and heart disease are related.

The chance of these consequences is decreased by keeping the HbA1C within a healthy normal range. It also enhances general well-being. Controlling your HbA1C or A1C levels requires regular monitoring, a healthy diet, and regular exercise. Follow your doctor's advice as well. It's to guarantee improved management of diabetes.

Among the most essential activities you can do to control diabetes is to regularly check your blood sugar levels. You'll get to see what makes your levels climb or fall. These include consuming various meals, taking insulin or medication, or exercising. 

FAQs

Can HbA1c detect prediabetes?

Prediabetes is defined as readings ranging from 5.7% to 6.4%. A HbA1c reading of 5.7- 6.5 is seen as a sign of prediabetes. Additionally, 6.5 or higher is considered diabetes.

What is the cost of an HbA1c test?

Location-specific, it usually falls between $10 and $50. Different Indian cities have varying prices. The cost of the HbA1c test might be a bit more expensive in urban areas compared to smaller towns. The high operational costs and cost of living are to blame for this. An alternative that fits your budget may always be found by comparing prices elsewhere.

Can HbA1c detect HIV?

No, it's unique to glucose levels. HIV detection is not correlated with HbA1c testing.

What is the HbA1c normal range?

Test results for HbA1C typically fall between 4.5% and less than 5.7%. The usual value ranges will change across pathology laboratories and hospitals. Your age and current medical problems may affect your value. It is thus always recommended that you speak with your healthcare professional following the test. 

How can I lower my HbA1c quickly?

Your HbA1c cannot be lowered rapidly. The procedure takes time to complete. In the past two to three months, this examination is capable of forecasting standard blood sugar levels. Therefore, lowering HbA1C fast is impossible. Your HbA1C will progressively drop with regular diabetes medication, exercise, and nutrition. The HbA1C result won't change much for two to three months.

What happens if HbA1c is high?

A severe HbA1c is a sign of a raised blood sugar level. This raises your chance of acquiring diabetes-related issues. These resemble severe issues with your feet and eyes.

What is the average HbA1c level based on age?

Normal HbA1c readings for various age groups are as follows:


  • 4.8%–5.7% of children and teenagers (6–17 years old)

  • Individuals aged 18–64 have 4.8%–5.7%

  • Adults (those 65 and up) have 5.7%–6.5% 


**Medical Disclaimer: The following information is for educational purposes only. No information provided on this website, including text, graphics, and images, is intended as a substitute for professional medical advice. Please consult with your doctor about specific medical advice about your condition(s).

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