What is a quadruple marker test in pregnancy?

A quadruple marker test in pregnancy is a blood test designed to check for the risk of birth defects. You should get a quadruple marker test done when you are at a higher risk of having a child with birth defects. It is also an important screening examination that all pregnant women should perform.

The quadruple marker test is performed during the second trimester of pregnancy, typically ranging from between 15 weeks and 20 weeks of pregnancy. It is an important test to check for the risk of Down’s syndrome, Edward’s syndrome, Spina bifida, abdominal wall defects, and other important conditions.

A normal test result indicates that you are having a baby with no risk of a birth defect as detected in the test.

The quadruple marker screen test checks your risk of having a baby with a birth defect. The quadruple marker test is designed to check for 4 key parameters. It tests for alpha-fetoprotein (AFP) and human chorionic gonadotropin (hCG). The screening examination also checks for uE3 and inhibin-A which are hormones produced by the placenta.

There are several conditions under which the test is highly recommended to pregnant women. These are as follows.

In the event that the woman is over the age of 35 years, the risk factor rises which is why the test is recommended.

If you have a chronic condition such as diabetes, and are pregnant then you should definitely get the quadruple marker screening performed.

If you have a family history of birth defects or cognitive developmental issues, then getting a screening test performed is important. 

It is important to get two other marker tests during the course of your pregnancy.

In a double marker test, the parameters of human chorionic gonadotropin (hCG) and pregnancy-associated plasma protein A (PAPP-A) are measured.

In a triple marker test, your levels of alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3) are checked.

Anomalies in these marker levels can provide a better insight into the risk factors of the foetus having developmental conditions. 

No you don't need any special preparations for the quadruple marker test.

You can acquire the quad marker test in India through MyDiagnostics.

You can get the quadruple marker test price via MyDiagnostics. The quadruple marker pregnancy test cost is INR 3000 for the second trimester test.

Yes, you can get an at-home sample collection done with your results emailed directly to you within 24-48 hours in most cases.

* Medical Disclaimer - The following information is for educational purposes only. No information provided on this website, including text, graphic, and images, are intended as substitutes for professional medical advice. Please consult with your doctor about specific medical advice pertaining to your condition(s).