1st and 2nd Trimester - Triple, Quadruple, and Double Marker Pregnancy Test
About the First and Second Trimester Pregnancy Test - Double marker, Triple marker, Quadruple marker
Double marker test: A double marker test is a screening test that is used to assess the risk of certain chromosomal abnormalities and birth defects in a developing fetus. The test is typically performed during the first trimester of pregnancy, and it measures the levels of two specific proteins in the mother's blood: human chorionic gonadotropin (hCG) and pregnancy-associated plasma protein A (PAPP-A). The levels of hCG and PAPP-A can be used to estimate the risk of certain chromosomal abnormalities, such as Down syndrome, trisomy 13, and trisomy 18.
Triple marker test: A triple marker test is a screening test that is used to assess the risk of certain chromosomal abnormalities and birth defects in a developing fetus. The test is typically performed during the second trimester of pregnancy, and it measures the levels of three specific substances in the mother's blood: alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3). The levels of AFP, hCG, and uE3 can be used to estimate the risk of certain chromosomal abnormalities
Quadruple marker test: A quadruple marker test is a screening test that is used to assess the risk of certain chromosomal abnormalities and birth defects in a developing fetus. The test is typically performed during the second trimester of pregnancy, and it measures the levels of four specific substances in the mother's blood: alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), unconjugated estriol (uE3), and inhibin A. The levels of AFP, hCG, uE3, and inhibin A can be used to estimate the risk of certain chromosomal abnormalities.
Accuracy and Results of Test
The results of a double/Triple/Quadruple marker test are typically reported as a risk ratio, which compares the level of the markers in the mother's blood to the levels typically seen in a normal pregnancy. If the risk ratio is higher than expected, it may indicate an increased risk of a chromosomal abnormality or birth defect. If the risk ratio is lower than expected, it may indicate a decreased risk of a chromosomal abnormality or birth defect.
How is Double, Triple, Quadruple marker test performed
- Blood Sample collection require in special tube 10 ml & by Prior appointment.
- We Required filled Test Requisition Form or prescription
Is Double, Triple, Quadruple marker test recommended for all pregnant women?
Recommends that all pregnant women be offered screening for chromosomal abnormalities, regardless of their age or risk factors. However, the double marker test is typically recommended for women who are at an increased risk of having a baby with a chromosomal abnormality, such as:
- Women who are 35 years of age or older at the time of delivery
- Women with a personal or family history of chromosomal abnormalities
- Women who have had a previous pregnancy with a chromosomal abnormality
- Women with certain medical conditions, such as diabetes or epilepsy
It is important to discuss the benefits and limitations of the double marker test with a healthcare provider to determine if the test is right for you.
About the Quality
Quality assurance is done at 3 levels
- Sample collection from home using one time sealed QR coded sterile kits and transportation to the lab including the temperature condition requirements
- Sample acceptance and QC at the lab
- Sample run at the NABL/CAP/ISO certified labs - Metropolis
Why should I get a double marker test?
Getting a double marker test during the right window is one of the most important things you need to do. The screening test will aid in the identification of specific conditions that your child could have. You can also be better prepared if your child will have a genetic condition. You should also get the quad screen test done during the 15 - 20 week period of pregnancy to continue screening for potential conditions.
Can a double marker test be done after 14 weeks?
The testing window for the double marker test during pregnancy is between 10 and 14 weeks. After that timeframe the accuracy of the testing protocol may not be consistent. The double marker test report is also most accurate within the 14 weeks period.
How is a double marker test done?
The blood sample is collected in a 10 ml streak tube, after which it is analysed for marker levels. The double marker test report is then generated which shows precise levels of hCG and PAPPa, to check for abnormalities.
How do I read a quadruple marker test result?
The quadruple marker test will show the ranges of the different markers, such as HCG, PAPPa, AFP, etc. which will be important to know whether the baby is healthy and free from chromosomal abnormalities. A quadruple marker test normal report should indicate all levels of the markers to be in the normal ranges. You can also review what your quadruple marker test positive means, and get further testing to check your risk factors.
Is a quadruple marker test necessary?
Yes, if you are at a higher risk of chromosomal abnormalities then you should get the quadruple screen test done. The quadruple marker screening is a blood test designed to also be a screening mechanism for all mothers.
Your quadruple marker test will also provide more details on potential conditions that you need to prepare for. It is a comprehensive screening test making it vital for women who may be at risk of the foetus developing chromosomal conditions.
What is a quadruple marker test in pregnancy?
A quadruple marker test checks for blood levels of markers AFP, estriol, hCG, and Inhibin-A, to check for the presence of chromosomal abnormalities. You can also get a double marker test in pregnancy screening or a triple marker test during the first few stages of your pregnancy.
You can get the best quadruple marker test cost and double marker test price when you opt to buy from MyDiagnostics. You can benefit from at-home testing as well, which makes the entire process more convenient.
Is a triple marker test necessary after a double marker test?
In the event that your double marker tests are inconclusive, your doctor may recommend a triple marker test in pregnancy screening. Sometimes the reports may not accurately show double marker test in pregnancy normal values, in which case your should get a test to check for triple marker test normal values.
The right approach is to continue getting screening examinations throughout the duration of your pregnancy. This ensures that any false positives or negatives can be ruled out of the testing protocol. You should also get tested if you have a family history of birth defects as well.
What is triple marker test during pregnancy?
Similar to how pregnant women need a double marker test in pregnancy, a triple marker test is also required for screening purposes. The testing parameters of alpha-fetoprotein, human chorionic gonadotropin and unconjugated estriol are checked within the triple marker test.
It is important to also know the difference between double marker and triple marker test packages. The gestational age for the triple marker test is between 15 to 20 weeks, which is a key point of difference between the two.
What is the triple marker test cost in India?
The triple marker test cost in India ranges from INR 2800 onwards. Depending on the type and number of tests required, you can add them to the cart directly on the page above. The triple marker test in pregnancy screening is vital for all expecting mothers, and the triple marker test price can be acquired when checking or selecting the appropriate test in the above list.
- The double marker, triple marker, and quadruple marker tests are designed to test for chromosomal abnormalities and genetic defects that may be present in the foetus.
- The test requires a sample of the mother's blood in a 10ml streak tube, which is tested in a NABL certified laboratory.
- Expecting mothers who may be at risk of genetic defects or chromosomal abnormalities for the foetus.
- Mothers with a family history of birth defects and genetic conditions.
- Screening test for all expecting mothers to prepare for potential defects and conditions.
- You should provide all details of any prescriptions, medication, and other medical information.
- No special instructions are required for the test. The sample collection will be done at home.