1st and 2nd Trimester - Triple, Quadruple, and Double Marker Pregnancy Test
Test Parameters
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About the First and Second Trimester Pregnancy Test - Double marker, Triple marker, Quadruple marker
Double marker test: A double marker test is a screening test that is used to assess the risk of certain chromosomal abnormalities and birth defects in a developing fetus. The test is typically performed during the first trimester of pregnancy, and it measures the levels of two specific proteins in the mother's blood: human chorionic gonadotropin (hCG) and pregnancy-associated plasma protein A (PAPP-A). The levels of hCG and PAPP-A can be used to estimate the risk of certain chromosomal abnormalities, such as Down syndrome, trisomy 13, and trisomy 18.
Triple marker test: A triple marker test is a screening test that is used to assess the risk of certain chromosomal abnormalities and birth defects in a developing fetus. The test is typically performed during the second trimester of pregnancy, and it measures the levels of three specific substances in the mother's blood: alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3). The levels of AFP, hCG, and uE3 can be used to estimate the risk of certain chromosomal abnormalities
Quadruple marker test: A quadruple marker test is a screening test that is used to assess the risk of certain chromosomal abnormalities and birth defects in a developing fetus. The test is typically performed during the second trimester of pregnancy, and it measures the levels of four specific substances in the mother's blood: alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), unconjugated estriol (uE3), and inhibin A. The levels of AFP, hCG, uE3, and inhibin A can be used to estimate the risk of certain chromosomal abnormalities.
Accuracy and Results of Test
The results of a double/Triple/Quadruple marker test are typically reported as a risk ratio, which compares the level of the markers in the mother's blood to the levels typically seen in a normal pregnancy. If the risk ratio is higher than expected, it may indicate an increased risk of a chromosomal abnormality or birth defect. If the risk ratio is lower than expected, it may indicate a decreased risk of a chromosomal abnormality or birth defect.
How is Double, Triple, Quadruple marker test performed
- Blood Sample collection require in special tube 10 ml & by Prior appointment.
- We Required filled Test Requisition Form or prescription
Is Double, Triple, Quadruple marker test recommended for all pregnant women?
Recommends that all pregnant women be offered screening for chromosomal abnormalities, regardless of their age or risk factors. However, the double marker test is typically recommended for women who are at an increased risk of having a baby with a chromosomal abnormality, such as:
- Women who are 35 years of age or older at the time of delivery
- Women with a personal or family history of chromosomal abnormalities
- Women who have had a previous pregnancy with a chromosomal abnormality
- Women with certain medical conditions, such as diabetes or epilepsy
It is important to discuss the benefits and limitations of the double marker test with a healthcare provider to determine if the test is right for you.
About the Quality
Quality assurance is done at 3 levels
- Sample collection from home using one time sealed QR coded sterile kits and transportation to the lab including the temperature condition requirements
- Sample acceptance and QC at the lab
- Sample run at the NABL/CAP/ISO certified labs - Metropolis