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Autism Spectrum Disorder are complex neurodevelopmental disabilities with onset before 36 months and characterized by impairments in reciprocal social interactions, verbal and non-verbal communication skills, interests and activities. Children and adolescents with autism vary widely in abilities, intelligence, and behaviors
ASD is known to be influenced by genetic and environmental factors. A range of gastrointestinal disorders have been linked in the pathophysiology of ASD and studies have found that the condition is associated with abnormal gut flora. There is also the possibility of previously unrecognized etiologic connections between dysbiosis and childhood developmental problems.
It has been observed that altered gut microorganisms produce toxic metabolites and are absorbed in the portal circulation and accumulate in the neural tissue. These metabolites interfere with the neurotransmitter metabolism and are excreted in large amounts in urine in children. Moreover, the effect of these metabolites manifests in autistic symptoms. Therefore urine metabolic analysis is used for diagnosis, treatment and prognosis of babies with autistic symptoms.
According to Centres of Disease Control, individuals with ASD often have problems with social, emotional, and communication skills. They might repeat certain behaviors and might not want change in their daily activities. Many people with ASD also have different ways of learning, paying attention, or reacting to things. Signs of ASD begin during early childhood and typically last throughout a person’s life.
Individuals with ASD if exposed to repeated courses of multiple antibiotic therapies may contribute to the complex relationships between gastrointestinal dysbiosis and ASD by altering the composition or stability of their normal microbial flora
Is autism genetic?
Recent studies have shown that though Autism is primarily a neurological disorder impairing language, communication and social skills, it may have an indirect genetic predisposition. The Center for Disease Control in the United States has estimated that 1 out of every 68 children will be diagnosed to be on the Autism Disorder Spectrum.
Is autism a neurological disorder?
Yes, Autism spectrum disorder (ASD) refers to a group of complex neurodevelopmental disorders characterized by repetitive and characteristic patterns of behavior and difficulties with social communication and interaction. The symptoms are present from early childhood and affect daily functioning.
Can autism be screened during pregnancy?No, Autism cannot be detected during pregnancy
What is asperger syndrome?Asperger’s syndrome (AS) is one of a group of neurological disorders known as autism spectrum disorders (ASDs). AS is considered to be on the mild end of the spectrum. People with AS exhibit three primary symptoms: