MyDiagnostics (NABL, CAP, ISO Lab)

Double, Triple & Quadruple Marker Test in Pregnancy – At Home

Test Parameters

Sample Required: Blood collected in Streak Tube - 10 ml.

Test Mode: At Home

Turn Around Time: 24-48 Days

Fasting Time: None

Other Instructions: We require Prescription for this test

Recommended for: First Trimester: 8 to 13 weeks, Second Trimester: 14 to 22 weeks.

About the First and Second Trimester Pregnancy Test - Double marker, Triple marker, Quadruple marker

Double marker test: A double marker test is a screening test that is used to assess the risk of certain chromosomal disorders, including common chromosomal abnormality, and the double marker test results for birth defects. in a developing fetus. The double marker test is typically performed during the first trimester of pregnancy, and it measures the levels of two specific proteins in the mother's blood: human chorionic gonadotropin (hCG) and pregnancy-associated plasma protein A (PAPP-A). The levels of hCG and PAPP-A can be used to estimate the risk of certain chromosomal abnormalities, such as down syndrome, and trisomy 13, and trisomy 18. trisomy 13, and trisomy 18.

Triple marker test: A triple marker test is a screening tool that detects chromosomal abnormalities and birth defects in a developing fetus. The test is typically performed during the second trimester of pregnancy for early detection , and it measures the levels of three specific substances in the mother's blood, aiding in the detection of neural tube defects : alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3). The levels of AFP, hCG, and uE3 can be used to estimate the risk of certain chromosomal abnormalities

Quadruple marker test: A quadruple marker test is a screening test that is used to assess the risk of chromosomal abnormalities and genetic disorders, including birth defects. in a developing fetus. The test is typically performed during the second trimester of pregnancy, and it measures the levels of four specific substances in the mother's blood: alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), unconjugated estriol (uE3), and inhibin A. The levels of AFP, hCG, uE3, and inhibin A can be used to estimate the risk of certain chromosomal abnormalities, including severe chromosomal disorders, which are critical for prenatal planning .

Accuracy and Results of Test

The results of a double/Triple/Quadruple marker test are typically reported as a risk ratio, which compares the level of the markers in the mother's blood to the levels typically seen in a normal pregnancy. If the risk ratio is higher than expected, it may indicate an increased high risk of a chromosomal abnormality or associated risks related to birth defects, leading to additional diagnostic tests. If the risk ratio is lower than expected, it may indicate a decreased risk of a chromosomal abnormality or birth defect, emphasizing the importance of early screening for risk assessment.

How is Double, Triple, Quadruple marker test performed

Blood Sample collection require in special tube 10 ml & by Prior appointment.
We Required filled Test Requisition Form or prescription

Is Double, Triple, Quadruple marker test recommended for all pregnant women?

Recommends that all pregnant women be offered screening for chromosomal abnormalities like down syndrome, regardless of their age or risk factors. However, the double marker test is typically recommended for women who are at an increased risk of having a baby with a chromosomal abnormality and may need further diagnostic tests, such as further testing based on the findings from the double marker test.

Women who are 35 years of age or older at the time of delivery
Women with a personal or family history of chromosomal abnormalities
Women who have had a previous pregnancy with a chromosomal abnormality
Women with certain medical conditions, such as diabetes or epilepsy

It is important to discuss the double marker test results interpretation, benefits, and limitations of the double marker test with a healthcare provider., especially for early medical intervention, to determine if the double marker test, a simple blood test, is right for you after discussing the double marker test procedure with your healthcare provider .

About the Quality

Quality assurance is done at 3 levels

Sample collection from home using one time sealed QR coded sterile kits and transportation to the lab including the temperature condition requirements
Sample acceptance and QC at the lab
Sample run at the NABL/CAP/ISO certified labs - Metropolis

Who is it for ?

What should I do after the test?

What will I discover through this test?

Guidelines

FAQs

Why should I get a double marker test?

Getting a double marker test during the right window is one of the most important things you need to do. The double marker test will aid in the identification and early detection of specific conditions, including neural tube defects, that your child could have. You can also be better prepared if your child will have a genetic condition. You should also get the quad screen test done during the 15 - 20 week period of pregnancy to continue screening for potential conditions.

Can a double marker test be done after 14 weeks?

The testing window for the double marker test performed during pregnancy is crucial. and should be conducted considering the gestational age, specifically between 10 and 14 weeks. After that timeframe, the accuracy of the double marker test protocol may not be consistent, which could lead to incorrect gestational age and affect the chances of receiving accurate results. The double marker test report is also
most accurate within the 14 weeks period.

How is a double marker test done?

The blood sample is collected in a 10 ml streak tube, after
which it is analysed for marker levels. The maternal serum screening double marker test report is then
generated which shows precise levels of hCG and PAPPa, to check for
abnormalities and is crucial for report generation .

How do I read a quadruple marker test result?

The quadruple marker test will show the ranges of the
different markers, such as HCG, PAPPa, AFP, etc. which will be important to
know whether the baby is healthy based on the quadruple marker test results. and free from chromosomal abnormalities, ensuring the baby's health . A
quadruple marker test normal report should indicate all levels of the markers
to be in the normal ranges. You can also review what your quadruple marker test
positive means, and get further testing to check your risk factors.

Is a quadruple marker test necessary?

Yes, if you are at a higher risk of chromosomal
abnormalities then you should get the quadruple screen test done. The quadruple
marker screening is a blood test designed to also be a screening mechanism for
all mothers and may lead to further diagnostic tests if necessary .

Your quadruple marker test will also provide more details on
potential conditions that you need to prepare for, especially if there is an increased risk of genetic conditions. . It is a comprehensive
screening test for genetic disorders, including chromosomal disorders, making it vital for women who may be at risk of the foetus developing chromosomal conditions to ensure a healthy pregnancy.

What is a quadruple marker test in pregnancy?

A quadruple marker test checks for blood levels of markers AFP, estriol, hCG, and Inhibin-A, to check for the presence of chromosomal abnormalities through a blood test. You can also get a double marker test in pregnancy screening or a triple marker test during the first few stages of your pregnancy to ensure accurate results.

You can get the best quadruple marker test cost and double marker test price when you opt to buy from MyDiagnostics. You can benefit from at-home testing as well, which makes the entire blood test process more convenient, including proper blood sample collection .

Is a triple marker test necessary after a double marker test?

In the event that your double marker tests are inconclusive, your doctor may recommend a triple marker test in pregnancy screening or further testing if needed, it may be beneficial to have a marker test be done. Sometimes the reports may not accurately show double marker test negative in pregnancy normal values, in which case your doctor may recommend additional diagnostic tests to check for triple marker test normal values.

The right approach is to continue getting screening examinations throughout the duration of your pregnancy. This ensures that any false positives or negatives can be ruled out of the risk assessment testing protocol. You should also get tested if you have a family history of birth defects as well, and consider further additional diagnostic tests .

What is triple marker test during pregnancy?

Similar to how pregnant women need a double marker test in pregnancy as part of routine prenatal care, a triple marker test is also required for screening purposes. The testing parameters, along with ultrasound findings of alpha-fetoprotein, human chorionic gonadotropin and unconjugated estriol, are checked within the triple marker test.

It is also important to know the difference between double marker and triple marker test packages. The gestational age for the triple marker test is between 15 to 20 weeks, which is a key point of difference
between the two.

What is the triple marker test cost in India?

The triple marker test cost in India ranges from INR 2800 onwards. Depending on the type and number of tests required, including double marker test results, you can add them to the cart directly on the page above if you are considered high risk. The triple marker test in pregnancy screening is vital for all expecting mothers, as it is a simple blood test, and the triple marker test price can be acquired when checking or selecting the appropriate test in the above
list.