Here's what a Quadruple Marker Test Positive means

A positive result on a quadruple marker test indicates that further testing may be required to confirm whether there is a birth defect or chromosomal abnormality. The out of normal range for the 4 test markers may not singularly indicate risk, but can enable doctors to run further specific testing.

Quad marker screening or a quad screen test can help in detecting the presence of Trisomy, Down syndrome, Neural tube defects, etc. through the blood test results. Doctors can check for the risk of birth defects by analysing the quad marker screen parameters.

By understanding what a quadruple marker test positive means, you can take the right steps to learn more about what risk factors may be present. Doctors may also recommend further testing if you have a family history of birth defects or chromosomal abnormalities. 

Through the checking of the different hormone produced across the 4 markers, the increased risk of birth defects and abnormalities can be analysed. Further tests may also be required if there is a positive result in a quad marker screen measure.

Unconjugated estriol (uE3), Alpha-fetoprotein (a protein produced by the baby's organs), Inhibin-A, and Human chorionic gonadotropin are checked in pregnant women to capture the risk profile. Your doctor will be able to make the final assessment of the right next steps.

Down syndrome can cause developmental delays, as well as intellectual disabilities in children, which is why it is a critical test for a complete prenatal protocol.

You can test for Trisomy 18, or Edward's syndrome, through the quad marker test. The condition can lead to slower development and abnormalities in the foetus and can be checked via the test.

The quad marker test can check for abdominal wall defects in foetuses, which is a critical prenatal testing protocol. You can also get the right results on any risk factor present with regards to future defects.

If you have a pre-existing condition or any other parameter that can affect the pregnancy, then you need to get the quad marker test done. The test may be highly recommended for pregnancies that are already at-risk.

A quad marker is a simple blood test that checks for the risk for birth defects via blood sample analysis. An abnormal quadruple marker test may indicate the presence of certain birth defects which may not be effectively captured in a double marker test.

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Your doctors may recommend further testing, both invasive and non-invasive, to get a better idea of the risk factors present after a positive quad result. You can also get these tests performed as a part of a routine analysis as well.

An ultrasound can help in determining the presence of any potential complications that may arise during the gestational period.

The amniotic fluid is studied from the uterus to check for potential signs of abnormalities and birth defects. This is a direct test that can be performed to check for signs of abnormalities more closely.

CVS is placental testing for chromosomal disorders and abnormalities, which is an important test that must be performed if a positive quad test is indicated.

NIPT can be done during the 10 week gestational period, and is a key test to determine the presence of abnormalities. While it can't check for all congenital disorders, it can test for the more common ones.

 *Medical Disclaimer - The following information is for educational purposes only. No information provided on this website, including text, graphic, and images, are intended as substitutes for professional medical advice. Please consult with your doctor about specific medical advice pertaining to your condition(s).