What is the double marker test in pregnancy?

Time to read 2 min

A double marker test is an examination of the foetus to detect the presence of chromosomal abnormalities. By checking for free Beta hCG (human chorionic gonadotropin) and PAPP-A (pregnancy-associated plasma protein-A) it can check for the risk potential of developmental syndromes.


The first trimester screening test is important for all mothers, especially if they are at a higher risk of having a child with a developmental disorder. You can get checked for your risk factor with ease, during the first trimester itself. It is also a critical screening examination that all pregnant women should take.

What is a chromosomal abnormality?

Within each cell there are 46 chromosomes present, with 23 matching pairs. While half the chromosomes are passed down from the mother, and the other half from the father, there may be abnormalities present within them.


Genetic disorders can be passed down in the foetus, which can impact the mental and physical development of the child. There can also be abnormalities present for the first time, without either parent having the risk factor present.


It is important to get a test done to determine whether the risk factor is present in the case of your pregnancy. A double marker test can be beneficial in determining the risk factor.

Why is a double marker test used?

A double marker test can be recommended by a doctor in the following cases.

Checking for Down syndrome

The test is an early marker test to check for Down syndrome.

Testing for physical ailments

The results for the double marker test can showcase risk of the child developing physical ailments long-term.

Analysing for birth defects

The test can check for Trisomy 18, which can be related to several birth defects and mental developmental issues.

Organ disorder issues

The test can detect Trisomy 21, which is related to organ health disorders in children.

General screening test

You may also want to opt for a double marker test as a regular screening test for your first trimester even if you don't have an inherent risk factor present.


What other marker tests are available for pregnant women?

There are two other critical marker tests that need to be done for foetus health assessment.

Triple Marker test

The markers alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3) are checked during the second trimester in the triple marker test.

Quadruple Marker test

You can perform the quadruple marker test by checking for levels of alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), unconjugated estriol (uE3), and inhibin A.



Where can I buy a double marker test in India?

The double marker test is a necessary pregnancy screening examination that all mothers need. The dual marker test is available in India through MyDiagnostics. You can place an order on our platform and receive the test for at-home sample collection. You can also get the results within 24-48 hours in most cases. 

What is the cost of the double marker test in India?

You can buy the double marker test in pregnancy examination for INR 2500 through MyDiagnostics. You can place an order easily via our platform. 


* Medical Disclaimer - The following information is for educational purposes only. No information provided on this website, including text, graphic, and images, are intended as substitutes for professional medical advice. Please consult with your doctor about specific medical advice pertaining to your condition(s).

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